Normally these files are associated with an httphandler and you can find them in the web.config and you can remove them from their:
Need help! How do I get my embedded scripts to be delivered by ScriptResource.axd handler? The new script tag is injected into the HTML where the first resource script was found.
scriptresource iis rewrite ... Get the actual error code 500.x from the IIS logs. If the page has a ScriptPlaceholder control (which should be a singleton, like the ScriptManager), output all script within that control;3. Then content is then aggregated into a single string which then get’s minified.
Unless you want to see the code to trace it back to something else? I can't set it on the